Experimental drug reduces protein clumps and slows memory loss in early Alzheimer's : latimes
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Experimental drug reduces protein clumps and slows memory loss in early Alzheimer's
Experimental drug reduces protein clumps and slows memory loss in early Alzheimer's
In the search for a treatment capable of changing the course of Alzheimer's disease, new findings are offering a rare glimmer of hope: In a preliminary trial of subjects suffering from memory and thinking problems or diagnosed with early Alzheimer's, a bioengineered medication called aducanumab has demonstrated the ability to clear accumulations of beta-amyloid proteins — a hallmark of Alzheimer's — from the brain.And compared with subjects receiving a placebo medication, those who got monthly infusions of aducanumab in high doses appeared to experience less progressive loss in mental function.The results of the early clinical trial, reported Wednesday in the journal Nature, offer new evidence that clearing amyloid plaques might be an effective strategy for preventing, halting or even reversing Alzheimer's dementia, especially if the degenerative brain disorder is detected and treated early.
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Scientists report success in trial of drug to fight Alzheimer's disease
Scientists report success in trial of drug to fight Alzheimer's disease
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Trial drug shows 'impressive' Alzheimer's action: study
Trial drug shows 'impressive' Alzheimer's action: study
PARIS - An experimental drug cleared protein buildup in the brains of people with mild Alzheimer's disease and slowed their mental decline, the results of a preliminary trial showed Wednesday.The drug, aducanumab, was tested for a year, raising hopes that a treatment may finally be within reach for Alzheimer's diseaseThe outcome raised hopes that a treatment may finally be within reach for the memory- and independence-robbing disease, but experts cautioned against overplaying the findings.The drug, aducanumab, is only the latest antibody to show promise in an early, Phase I drug trial, they said.
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New Alzheimer's drug clears abnormal protein clogs in small, promising trial
New Alzheimer's drug clears abnormal protein clogs in small, promising trial
BY KAREN WEINTRAUB, Scientific AmericanA new drug trial that some researchers are calling the most promising yet in the fight against Alzheimer's suggests it may be possible to clear the brain of the amyloid protein that is characteristic of the disease.The results are very impressive and very encouraging.The study was small and researchers caution that it's far too soon to declare victory against a fatal disease that robs people of their memories and ability to function in daily life.
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Alzheimer's drug study gives 'tantalising' results
Alzheimer's drug study gives 'tantalising' results
Image copyright ALFRED PASIEKA/SCIENCE PHOTO LIBRARYA drug that destroys the characteristic protein plaques that build up in the brains of patients with Alzheimer's is showing "tantalising" promise, scientists say.Experts are cautious because the drug, Aducanumab, is still in the early stages of development.But a study in Nature has shown it is safe and hinted that it halts memory decline.
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